Natural Molecules as Dietary Support for FXTAS Patients

Interview of Professor Peng Jin and Professor Pietro Chiurazzi

Thursday, 23rd June 2022, at Press Room of the Chamber of Deputies, Rome

On June 23rd 2022, an important event for the presentation of the innovative spin-off, MagisNat, American branch of MAGI group, will be held at the Press Room of the Italian Chamber of Deputies in Rome from 04:00 p.m. to 06:00 p.m.
This event will gather many researchers and professors, both Italian and American, who will have the opportunity to discuss very important and topical matters: the Mediterranean diet and its importance; natural molecules and the promotion of supplements to make up for nutritional deficiencies, due to an incorrect and unbalanced lifestyle; the importance of a healthy, genuine and low-fat diet that leads to people’s well-being.
Among the guests of this event there are Professor Peng Jin (Department of Human Genetics, School of Medicine at Emory University, Atlanta, USA), who will connect directly from America, and Professor Pietro Chiurazzi, (Fondazione Policlinico Universitario Agostino Gemelli IRCC, Department of Medical Genetics, Rome, Italy), who will participate in presence. Their intervention will concern the primary role that the use of natural molecules with anti-inflammatory and antioxidant properties, in the context of food supplementation, could have in treating neurodegenerative diseases, especially in Fragile X syndrome with tremor/ataxia (FXTAS).
FXTAS syndrome is a rare neurodegenerative disorder, characterized by adult-onset, progressive intention tremor, and ataxic gait. Furthermore, individuals with a premutation in the FMR1 gene are at increased risk of developing this syndrome.
As previously mentioned, the two professors are carrying out in vitro and in vivo studies on candidate natural compounds for the treatment of this neurodegenerative disease. Among these compounds, we can mention olive polyphenols, such as hydroxytyrosol, which are known for their antioxidant and anti-inflammatory properties, which in the context of a balanced dietary supplement could play a primary role in FXTAS syndrome.
There is still a lot to discover about these molecules with beneficial effects for living organisms, but there are good conditions for obtaining results leading to developments in science and research.
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